I'd say the jetting would have to be off.
When I was talking to Q about the jetting he told me that the Keihin are picky on jetting, and the 250's are picky on being jetted and when you put the two together they are even worse on being picky and he also went on to say that the air/fuel screw on the Keihin doesn't do much for tuning, you've gotta have the pilot as close to dead on as possible.
Again, I've not started messing with my PJ yet because cold weather, wanting to get my bike back together to go play,, that's just what Q told me while I was talking to him.
Side note: my bike, with the TM34 and jetting it's got now, will go piiigggg rich from just sitting and idling or being under 1/2 throttle for too long. I've gotta hammer on it to get it good and crisp again