In the end you'll wind up with the same HP, there's a limit on the power that a 500 can make before it blows up so you'll hit the same reliability wall as you would with other methods.
Takes a lot more tuning with nitrous and it can be harder on the engine vs. a ported/piped combo.
You'll save money, but only if you don't destroy the engine in the process of tuning it, and the expense of running nitrous is something you have to figure in too.
The only kind of nitrous system you should be running is a wet system (meters additional fuel in with the nitrous) because otherwise you'll melt the piston before you reach the end of the strip.
It might also change what class you get to run with your quad at a drag, and if that puts you in a league that you really don't want to be in, well...I guess you'll have to get used to losing with a fast LT